To prepare and submit Sulphanilamide from acetanilide – Practical Medicinal Chemistry

 Aim: To prepare and submit Sulphanilamide from acetanilide. Requirements: Beaker, funnel, conical flask, Buchner funnel, acetanilide, chlorosulphonic acid, aqueous ammonia. Theory: For the preparation of sulphanilamide, acetanilide is treated with chlorosulphonic acid, which forms p-acetamidobenzene sulphonyl chloride, which on treatment with ammonia gives p-acetamidobenzene sulphonamide, followed by hydrolysis. Reactions involved: Step-I: Synthesis of p-acetamido benzene sulphonyl chloride: Step-II: Synthesis of p-acetamido benzene sulphonamide: Step-III: Synthesis of Sulphanilamide: Procedure: Step 1: Synthesis of p-acetamidobenzene sulphonyl chloride: Take 25 g powdered acetanilide in a two mouth round bottom flask fitted with dropping…

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Steroidal Nomenclature – Medicinal Chemistry B.Pharmacy 5th Semester

Steroidal Nomenclature and Structure of Steroids, Stereochemistry Steroidal Chemistry is an important part of syllabi in Medicinal Chemistry II, B Pharmacy 5th semester. In This article you came to know about some important basic concepts of Steroidal Nomenclature. Here we will discuss some common structure and Stereo Chemistry of some important steroids. Gonane, Estrane, Pregnane, Androstane, Cholane, Cholestane. Content Uploaded By: Mr. Rajesh Sukhija (Pharmacist), PGIMS Rohtak.  

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Physicochemical properties in relation to biological action, Unit-I B.Pharm 4th Semester Notes PDF

  Introduction to Medicinal Chemistry History and development of medicinal chemistry Physicochemical properties in relation to biological action Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism. Drug metabolisam Drug metabolism principles- Phase I and Phase II.  Factors affecting drug metabolism including stereo chemical aspects Introduction to Medicinal Chemistry History and Development of Medicinal Chemistry Physicochemical properties in relation to biological action Ionization Solubility Partition Coefficient Hydrogen bonding Protein binding Chelation Bioisosterism Optical and Geometrical isomerism

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History and Development of Medicinal Chemistry, Unit-I B.Pharmacy 4th Semester Note PDF

Introduction to Medicinal Chemistry History and development of medicinal chemistry Physicochemical properties in relation to biological action Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism. Drug metabolisam Drug metabolism principles- Phase I and Phase II.  Factors affecting drug metabolism including stereo chemical aspects Introduction to Medicinal Chemistry History and Development of Medicinal Chemistry 3500 BC – Sumerians reported use of opium3000 BC – Chinese reported use of ephedra (Ma Huang)1793 – Faureroy and Vauquehin established the Ecole Supurieure de Pharmacie i.e. first to incorporate chemistry into pharmacy curriculum. 1803 –…

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Introduction to Medicinal Chemistry, Unit-I B.Pharmacy 4th Semester Notes PDF

  Introduction to Medicinal Chemistry History and development of medicinal chemistry Physicochemical properties in relation to biological action Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism. Drug metabolism Drug metabolism principles- Phase I and Phase II.  Factors affecting drug metabolism including stereo chemical aspects Introduction to Medicinal Chemistry Medicinal chemistry is the chemistry discipline concerned with the design, development and synthesis of pharmaceutical drugs. The discipline combines expertise from chemistry and pharmacology to identify, develop and synthesize chemical agents that have a therapeutic use…

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Cholinergic Drugs Important GPAT Pharmacy MCQs

Medicinal Chemistry Multiple Choice Questions Click START button below. Here we have designed the few MCQ for GPAT and NIPER aspirants and may be useful. Test questions will be updated regularly. Start Quiz Total Score Question Question Option a Option b Option c Option d Correct Answer Wrong answer Next This quiz tools is designed by HK Technical. If you want to install it on your website please contact us.

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Drug Receptor Interaction MCQs Medicinal Chemistry

Medicinal Chemistry Important MCQs on Drug Receptor Interaction Here are some Important Question from Medicinal Chemistry In B Pharmacy 4th semester. In This article you came to know about some important Questions on Drug Receptor Interaction Part I. We have divided these in different parts. Here we will discuss some common. ……………………….. Here You can take a test on content given below. Start Quiz Total Score Question Question Option a Option b Option c Option d Correct Answer Wrong answer Next This quiz tools is designed by HK Technical. If…

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Heterocyclic Nomenclature Some Common Structure Medicinal Chemistry

Structure of Some Common Heterocyclic Compounds Medical Organic Chemical Basic. Medicinal Chemistry In B Pharmacy 4th semester, started from these stuff. In This article you came to know about some important basic concepts of Heterocyclic Nomenclature. Here we will discuss some common structure of Heterocyclic Chemistry.  Content Uploaded By: Nakul Saini (Pharmacist), PGIMS Rohtak.

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Unit-I Introduction to Medicinal Chemistry – Medicinal Chemistry I

Content: Introduction to Medicinal Chemistry History and development of medicinal chemistry Physicochemical properties in relation to biological action Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism. Drug metabolism Drug metabolism principles- Phase I and Phase II.  Factors affecting drug metabolism including stereo chemical aspects Introduction to Medicinal Chemistry Medicinal chemistry is the chemistry discipline concerned with the design, development and synthesis of pharmaceutical drugs. The discipline combines expertise from chemistry and pharmacology to identify, develop and synthesize chemical agents that have a therapeutic…

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