Category: Pharmaceutical Biochemistry

Enzymes Introduction, properties, nomenclature and IUB classification of enzymesEnzyme kinetics (Michaelis plot, Line Weaver Burke plot)Enzyme inhibitors with examplesRegulation of enzymes: enzyme induction and repression, allosteric enzymes regulationTherapeutic and diagnostic applications of enzymes and isoenzymes Coenzymes –Structure and biochemical function Download

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Nucleic acid metabolism and genetic information transfer Biosynthesis of purine and pyrimidine nucleotides, Catabolism of purine nucleotides and Hyperuricemia and Gout disease, Organization of mammalian genome, Structure of DNA and RNA and their functions, DNA replication (semi conservative model), Transcription or RNA synthesis, Genetic code, Translation or Protein synthesis and inhibitors BP203T Biochemistry Notes All Chapters Download

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   Biochemistry deals with complete understanding of the molecular levels of the chemical process associated with living cells. The scope of the subject is providing biochemical facts and the principles to understand metabolism of nutrient molecules in physiological and pathological conditions. It is also emphasizing on genetic organization of mammalian genome and hetero & autocatalytic functions of DNA.   Objectives: Upon completion of course student shell able to 1. Understand the catalytic role of enzymes, importance of enzyme inhibitors in design of new drugs, therapeutic and diagnostic applications of enzymes.…

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Bioenergetics Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential. Energy rich compounds; classification; biological significances of ATP and cyclic AMP BP203T Biochemistry Notes All Chapters Download Most Important Questions: Describe: Bioenergetics Gibbs Free Energy Enthalpy Entropy Redox Potential Endergonic reactions Exergonic reactions Bioenergetics,Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential. Energy rich compounds; classification; biological significances of ATP and cyclic AMP,amino acids,nucleic acids,proteins,proteins and amino acids,nucleic acids and nucleotides,proteins made of amino…

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Biomolecules Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins. BP203T Biochemistry Notes All Chapters Download Carbohydrates: Most Important Questions: Define carbohydrates. Give their classification. What are polysaccharides? Classify them. Explain biological roles of carbohydrate. Differentiate between starch and glycogen. Write notes on :  Cellulose Anomers Epimers Mutarotation Inulin Homopolysaccharides Heteropolysaccharides Hyaluronic acid Chondroitin sulfates  Heparin Glycoaminoglycans Optical isomerism Lipids Most Important Questions: What are lipids? Classify them. Define biological role of lipids. What are fatty acids? Classify them. Describe briefly: Classification of…

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Amino acid metabolism General reactions of amino acid metabolism: Transamination, deamination & decarboxylation, urea cycle and its disorders Catabolism of phenylalanine and tyrosine and their metabolic disorders (Phenyketonuria, Albinism, alkeptonuria, tyrosinemia) Synthesis and significance of biological substances; 5-HT, melatonin, dopamine, noradrenaline, adrenaline Catabolism of heme; hyperbilirubinemia and jaundice BP203T Biochemistry Notes All Chapters Download Most Important Questions: What are proteins? Classify proteins based on their solubility. What are amino acids? Classify them. Discuss briefly: Quaternary structure of proteins Biological role of amino acids Essential amino acids Branched chain amino acid…

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Lipid metabolism β-Oxidation of saturated fatty acid (Palmitic acid) Formation and utilization of ketone bodies; ketoacidosis De novo synthesis of fatty acids (Palmitic acid) Biological significance of cholesterol and conversion of cholesterol into bile acids, steroid hormone and vitamin D Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity. BP203T Biochemistry Notes All Chapters Download Lipid Metabolism Important Questions: More important questions: scroll down. lipid metabolism,metabolism,fat metabolism,fatty acid metabolism,lipoprotein metabolism,lipid metabolism mcqs,lipids,mcqs on lipid metabolism,define lipid metabolism,what is lipid metabolism,dietary fat metabolism,explain lipid metabolism,meaning of lipid metabolism,learn about lipid…

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Biological oxidation Electron transport chain (ETC) and its mechanism. Oxidative phosphorylation & its mechanism and substrate level phosphorylation Inhibitors ETC and oxidative phosphorylation/Uncouplers BP203T Biochemistry Notes All Chapters Download Important Questions: Explain the process of oxidative phosphorylation and its inhibitors. Outline respiratory chain. Depict the sites of ATP production. Discuss briefly: Oxidative Phosphorylation Mitochondria respiratory chain Inhibitors of the electron transport chain Malate aspartate shuttle Glycerolphosphate shuttle Inhibitors and uncouplers of oxidative phosphorylation Write notes on: Respiratory chain Oxidative phosphorylation Substrate level phosphorylation Reducing equivalents Iron-sulfur centers Cytochromes P/O ratio…

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Carbohydrate metabolism Glycolysis – Pathway, energetics and significance Citric acid cycle- Pathway, energetics and significance HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase (G6PD) deficiency Glycogen metabolism Pathways and glycogen storage diseases (GSD) Gluconeogenesis- Pathway and its significance Hormonal regulation of blood glucose level and Diabetes mellitus BP203T Biochemistry Notes All Chapters Download Carbohydrates  Most Important Questions: Outline reactions of the citric acid cycle. Give energetic of the cycle and explain amphibolic role of the cycle. Outline hexose monophosphate shunt reactions. Discuss biological significance of the shunt. Give outline of glycolysis.…

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